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CREAMS


CREAMS

  • Creams are semisolid emulsion dosage forms.

  • They often contain more than 20% water and volatiles, and/or typically contain less than 50% hydrocarbons, waxes, or polyols as the vehicle for the drug substance.

  • Creams are generally intended for external application to the skin or to the mucous membranes.

  • Creams have a relatively soft, spreadable consistency and can be formulated as either a W/O emulsion (e.g., Cold Cream or Fatty Cream as in the European Pharmacopoeia) or as an O/W emulsion (e.g., Betamethasone Valerate Cream).

  • Creams are generally described as either nonwashable or washable, reflecting the fact

  • that an emulsion with an aqueous external continuous phase is more easily removed than one with a nonaqueous external phase (W/O emulsion).

Refer Emulsions



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